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Basic Information about Membranous Nephropathy

Basic Information about Membranous Nephropathy
Membranous Nephropathy refers to a kidney disorder, in which the glomeruli in kidneys became inflamed. In this article, we will introduce basic information about this disease.

Causes

Frankly speaking, it can be divided into two categories: both idiopathic and secondary.

In normal case, the immune system can help fight against various antigens. However, in membranous nephropathy, antibodies released by the abnormal immune system will combine with infections or bacteria, leading to immune complexes. Gradually, inflammatory reaction will be activated, causing damage to the filtering units called glomeruli.


In addition, the following factors are also related to this disease. Such as, certain drugs, infections, Systemic Lupus Erythematosus(SLE) and other autoimmune diseases. 

Symptoms

Generally speaking, protein in urine can be the first sign of MN. Except for this, patients may also experience some of the following symptoms, such as, blood in urine, swelling, frequent urination at night, loss of appetite and so on.

Complications

It is a common cause of nephrotic syndrome, which is characterized by swelling, massive proteinuria, hypoalbuminemia and hyperlipidemia. Except for this, infections, high blood pressure, chronic kidney failure, acute kidney failure and other complications can also be common complications.

Treatments

Medications like ACEI or ARBs to help lower hypertension, and the blood pressure level should be restricted within 130/80 mm Hg; Diuretics to help excrete toxins deposited in the blood and eliminate symptoms like swelling, etc; Enough supply of calorie; well control of cholesterol level.

Immunotherapy, as a systematic therapy, it aims at both correcting the abnormal immune system and restoring kidney function. For more information about this disease, you can send us an email:kidneyfight@hotmail.com and we will reply you within 48 hours.

If you happen to be a person with membranous nephropathy, we really hope the above basic information can be helpful. Any questions, you can consult with our online doctor directly. Good luck!

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