“I am IgA Nephropathy patients, with the development of the disease, I suffer more and more serious high blood pressure. And today my blood pressure even raise to 220/140. I just want to know the cause and management.”. Today we received the question and now we will have a introduction about the cause and management for IgA Nephropathy with high blood pressure.
The cause of high blood pressure in IgA Nephropathy:
1. the injured kidney fail to excrete the extra water and sodium out of body, the water and sodium retention in blood vessels can increase the blood volume, leading to high blood pressure. At the same time, water and sodium retention can increase the thickness of vascular smooth muscle cells. With the vessel wall thickening and vascular elasticity down, patients would suffer serious high blood pressure.
2. Kidney hypoxic-ischemic can stimulate the renin and angiotensin secretion, which lead to arterial wall contraction of whole body, causing high blood pressure; and the secretion of renin and angiotensin can cause further water and sodium retention.
3. The injured kidney fail to release enough vasorelaxant substances, which also is a cause of high blood pressure.
The management for IgA Nephropathy patients with high blood pressure:
ACEI is the common medicine in treating high blood pressure therough inhibiting the formation of angiotensin. But the long time use of the medicine is bad for the heart function, for IgA Nephropathy, the medicine also can decrease the GFR in some degree. Patients who want to get rid of the high blood pressure caused by kidney damage need solve the blood circulation condition in kidneys and improve the GFR. Micro-Chinese Medicine osmotherapy has functions of expending blood vessels, anti-inflammation, anti-freezing and degrading extra cellular matrix , so that it can block kidney damage and reverse kidney function effectively.
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