As for IgA nephropathy patients, when the glomerular filtration rate (GFR) is less than 10%, it means kidney condition has aggravated to the end stage renal disease (ESRD). In this case, patients usually are suggested to take kidney transplant. However, is it necessary?
Whether IgA nephropathy patients with GFR less than 10% need transplant?
Glomerular filtration rate refers to the amount of blood filtered by glomerulus per minute. Kidney diseases can be divided into five stages according to GFR. For IgA nephropathy, in the end stage the residual renal functions are not enough to maintain the basic life of patients, which forces patients to take some measures to prolong their life expectancy. Kidney transplant is one treatment choice to provide an opportunity for patients save their kidney and live better life.
However, IgA nephropathy is caused by immune disorder. The abnormal immune system may cause immune complexes deposit in the new kidney and make the transplanted kidney losses functions again. According to the clinical research, the relapse of IgA nephropathy is high after kidney transplant
Is there any alternative of transplant for IgA nephropathy?
As a matter of fact, if patients still have urine output, our experts of Huaxia Kidney Disease Hospital suggest the patients take Immunotherapy, which is mainly composed by six steps: accurate diagnosis, immune blocking, immune tolerance, immune regulation, immune clearance, and immune protection. This therapy can help clear immune complexes, regulate immune system, and repair damaged kidney tissues and cells from the origin.
But, if patients do not have urine volume any more, they can have a try with Stem Cell Therapy. It can help patients rebuild kidney structures and improve the patients’ condition effectively.
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