In HuaxiaKidney Disease Hospital, experts with many years' clinical experiences focus extraordinary expertise on each patient. Your care is carefully planned to address your needs and to ensure you receive the most advanced treatment without any side effects to your body.
Our hospital is known nationwide as the largest kidney disease specialized hospital. We have the newest approaches that have enabled thousands of patients with kidney disease to avoid dialysis and enjoy a better quality of life.
We take team approach to Focal Segmental Glomerulosclerosis (FSGS) care, providing comprehensive, yet highly specialized, treatment. Our team of specialized doctors, as well as support stuff including nurses, psychological consultant, dietitians and many others, work closely together-and with you-to give you higher chance for successful treatment.
As the largest kidney disease specialized hospital, HuaxiaKidney Disease Hospital is a leading institute for looking into new methods of kidney disease diagnosis and treatment. You benefit from the most advanced research and get recovered more quickly.
Early and accurate diagnosis of Focal Segmental Glomerulosclerosis (FSGS) helps you have the highest chance for successful treatment. Our experts are among the most experienced in the country at recognizing FSGS. These specialists use the most advanced technology and techniques to pinpoint FSGS.
FSGS Diagnostic Tests
If you have symptoms that may signal FSGS, your doctor will examine you and ask you questions about your health and your family medical history.
Urine protein, red blood cells and 24-hour urine collection reveal state of your kidney. Urine with dextrose, amino acid, and phosphate inflects renal injury in tubular area. Elevation in level of IgM is also a sign of FSGS.
● Blood Test
Serum Creatinine or Creatinine Clearance is usually in or close to the reference range in the early stage of FSGS.
● Renal Biopsy
Renal biopsy is used to confirm whether glomerular area is scarred. Compared with other test methods, renal biopsy is considered as exact index. Even so, sometimes you may need to repeat kidney biopsy, because finding affected section of glomeruli is a matter of chance, especially in the early stage of FSGS.
Focal Segmental Glomerulosclerosis (FSGS) is a disease that causes urinary loss of protein and eventual scarring of the glomerular filters of the kidney.
FSGS can develop as an isolated kidney disease (primary FSGS), and the cause of the disease is unknown.
FSGS can also occur due to other causes (secondary FSGS). In these cases, the disease can be caused due to:
1. Born with too few glomeruli.
2. Massive obesity.
3. Infections such as HIV, parvovirus, and hepatitis B.
4. Medications, or toxins.
5. Chronic systemic diseases and other chronic kidney diseases, such as sickle cell nephropathy.
Primary FSGS can affect people of all ages. It is an important cause of kidney problems in children. In adults, it is also increasingly seen. It occurs more frequently in black individuals compared to whites and is more frequent in males.
Focal Segmental Glomerulosclerosis (FSGS) causes inadequate filtering of waste products from the blood stream which in return lead to the following symptoms:
● Proteinuria-Leakage of large amount of protein into the urine
● Swelling, or edema around the eyes, hands and feet
● Hypertension-high blood pressure
● Hypoproteinemia-low protein levels in the blood
● Hypercholesterolemia-high cholesterol level in the blood
● Decreased urine output
● Nausea, and vomiting
● Weight gain
● Loss of appetite
HuaxiaKidney Disease Hospital is committed to providing you with the most-advanced treatments for Focal Segmental Glomerulosclerosis (FSGS) without any side effects to your body. Your FSGS treatment is customized specifically for you by one of the world's foremost teams of kidney experts.
We offer the most-advanced treatment option for FSGS-immunotherapy. It includes:
Newest immunosuppressive agents
There are excessive immune reaction within the body of FSGS patients. These medicines can help inhibit undue inflammatory response in FSGS so as to block further damages to the glomeruli and further loss of kidney function.
Micro-Chinese Medicine Osmotherapy
Based on traditional Chinese medicine, Micro-Chinese Medicine Osmotherapy is developed by our experts. The medicines are abstracted from Chinese herbal plants, so this is a natural treatment without any side effects to the body. This therapy can take effect to degrade immune complex and extracellular matrixes, anti-inflammation, improve the blood circulation in the kidneys and prevent the formation of thrombosis. Besides, special materials contained in this therapy can provide abundant nutrients to speed up the repairing of kidney function as well as enhance the immunity of the whole body.
To clear up the immune complexes completely, immunoadsorption, plasma exchange, and blood purification can be applied based on individual illness condition.
Focal Segmental Glomerulosclerosis (FSGS) diet is an essential component of ideal treatment that a patient can easily and readily implement.
A small amount of water intake should be listed in your diet plan, because much fluid will be out of damaged kidneys' control. Water restriction can contribute to balancing body fluids and remedying generalized swelling. Some fruits like grapes, berries and watermelon can be ate when you are thirsty.
Intake of protein plays a major role in FSGS diet, which can be used to reimburse the large amount loss of protein. However, you should avoid excessive amount of protein food, which may increase the burden of the impaired kidneys.
Symptoms like high blood pressure and edema can be aggravated by too much sodium intake, so you need avoid eating salty foods, such as salted drinking, pickles, walnuts, and sated cashew nuts and so on.
● Low-fat and low-cholesterol
Limit whole eggs to 2 per week, use egg substitutes or whites only; Use lean meats, well trimmed, poultry w/o skin, fish, shellfish, beans, nuts; Use healthy oils such as olive, canola, safflower, sunflower; Limit saturated fats (dairy, animal fat) and eliminate trans fat (partially hydrogenated oils found in processed and fast food).
Focal Segmental Glomerulosclerosis (FSGS) affects both children and adults. Men and boys are affected slightly more often than women and girls, and it also occurs more often in African Americans.
FSGS is sometimes linked to a hereditary gene. Having a family member with FSGS may increase the chance of acquiring the disease. Some of the genes known to be associated with FSGS are alpha actinin, WT1, and podocin.
Known causes include:
* Heroin use
* Inherited genetic problems
* Reflux nephropathy (a condition in which urine flows backward from the bladder to the kidney)
* Sickle cell disease
1. Do proper physical activity regularly.
2. Keep a healthy weight, and lose weight if necessary.
3. Tell your doctor if you have a family history of FSGS or other kinds of kidney disease, and then he can watch for signs for this disease.
Since idiopathic FSGS is difficult to treat, most patients with FSGS develop to total kidney failure in 5~20 years. Some patients with an aggressive form of FSGS reach total kidney failure in 2 to 3 years.
FSGS prognosis can be affected by factors like clinical manifestations, pathological changes of kidney tissue and curative effect of treatment.
● Clinical manifestations
⑴ If FSGS patients are accompanied with persistent Nephrotic Syndrome, the survival rate for about 10 years is 45%, while the non Nephrotic Syndrome patients can achieve 90%.
⑵ The prognosis is bad for patients with severe hyperlipidemia (high cholesterol) and severe proteinuria (>10g/24h).
● Pathological changes
If the pathological change of FSGS kidney disease is accompanied with diffuse mesangial proliferation, obvious arteriolosclerosis, renal tubule interstitial infiltration of inflammatory cells and interstitial fibrosis changes, the prognosis is bad.
● Curative effect of treatment
Treatment involving steroids or other immunosuppressive drugs appears to help patients by reducing proteinuria and improve kidney function. But these treatments are beneficial to only a minority of patients in whom they are tried, and some patients may have even poorer kidney function as well as poor prognosis.